Imbalance of the CD226/TIGIT Immune Checkpoint Is Involved in the Pathogenesis of Primary Biliary Cholangitis

The relationship between the cluster of differentiation 226 (CD226)/T cell Ig and ITIM domain (TIGIT) immune checkpoint and primary biliary cholangitis (PBC) pathogenesis is unknown. Herein, PBC patients (n = 42) showed significantly higher proportions of peripheral CD8(+) T and CD4(+) T cells expre...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Deng, Chuiwen, Li, Wenli, Fei, Yunyun, Wang, Li, Chen, Yingying, Zeng, Xiaofeng, Zhang, Fengchun, Li, Yongzhe
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7393007/
https://ncbi.nlm.nih.gov/pubmed/32793241
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.01619
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