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The CD226/CD155 interaction regulates the pro-inflammatory (Th1/Th17)/ anti-inflammatory (Th2) balance in humans
CD226 costimulatory signals strongly promote Th1 differentiation enhancing IFN(γ) production by naïve T cells. We recently reported that knockdown of CD226 on human T cells resulted in a decrease in T-bet and IFN(γ) expression. However, the role of CD226 on Th2 and Th17 cells remains unknown. Here,...
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| Autori principali: | , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2013
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3819731/ https://ncbi.nlm.nih.gov/pubmed/23980210 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1300945 |
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