TIM-3 is Expressed on Activated Human CD4+ T Cells and Regulates Th1 and Th17 Cytokines

TIM-3 is a molecule selectively expressed on a subset of murine IFNγ-secreting Th1 cells but not Th2 cells, and regulates Th1 immunity and tolerance in vivo. At this time little is known about the role of TIM-3 on human T cells. To determine if TIM-3 similarly identifies and regulates Th1 cells in h...

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Main Authors: Hastings, William D., Anderson, David E., Kassam, Nasim, Koguchi, Ken, Greenfield, Edward A., Kent, Sally C., Zheng, Xin Xiao, Strom, Terry B., Hafler, David A., Kuchroo, Vijay K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2759376/
https://ncbi.nlm.nih.gov/pubmed/19676072
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.200939274
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