“Tim-4 expressed on antigen-presenting cells induces T cell expansion and survival”

TIM (T-cell, immunoglobulin, mucin) proteins can regulate T cell immune responses. Tim-4 mRNA is not expressed in T cells, but exclusively in antigen-presenting cells. Tim-4 is a ligand for Tim-1 and Tim-4.Ig fusion protein was shown to either inhibit or expand T cells. However, the molecular basis...

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Main Authors: Rodriguez-Manzanet, Roselynn, Meyers, Jennifer Hartt, Balasubramanian, Savithri, Slavik, Jacqueline, Kassam, Nasim, Dardalhon, Valerie, Greenfield, Edward A., Anderson, Ana C., Sobel, Raymond A., Hafler, David A., Strom, Terry B., Kuchroo, Vijay K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2948965/
https://ncbi.nlm.nih.gov/pubmed/18354194
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