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TIMs: central regulators of immune responses

Exhaustion of T cell responses during chronic viral infections has been observed in both mouse and man and has been attributed to up-regulation of PD-1 on the surface of exhausted T cells. In patients with chronic human HIV infection, T cell exhaustion leads to opportunistic infections associated wi...

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Detaylı Bibliyografya
Asıl Yazarlar: Hafler, David A., Kuchroo, Vijay
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: The Rockefeller University Press 2008
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2585854/
https://ncbi.nlm.nih.gov/pubmed/19015312
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20082429
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