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TIM Family Proteins Promote the Lysosomal Degradation of the Nuclear Receptor NUR77
T cell immunoglobulin and mucin domain (TIM) proteins are cell-surface signaling receptors in T cells and scavenger receptors in antigen-presenting cells and kidney tubular epithelia. Here, we demonstrated a function for TIM proteins in mediating the degradation of NUR77, a nuclear receptor implicat...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3767312/ https://ncbi.nlm.nih.gov/pubmed/23233528 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.2003200 |
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