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Structure of mammalian endolysosomal TRPML1 channel in nanodiscs
Transient receptor potential mucolipin 1 (TRPML1) is an endo/lysosomal cation channel ubiquitously expressed in mammalian cells(1,2) and its loss-of-function mutations are the direct cause of Type IV mucolipidosis (MLIV), an autosomal recessive lysosomal storage disease(3-6). Here we present the sin...
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| Publicado no: | Nature |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5901962/ https://ncbi.nlm.nih.gov/pubmed/29019981 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature24035 |
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