Clinical impact of endometrial cancer stratified by genetic mutational profiles, POLE mutation, and microsatellite instability

BACKGROUND: The molecular characterization of endometrial cancer (EC) can facilitate identification of various tumor subtypes. Although EC patients with POLE mutations reproducibly demonstrate better prognosis, the outcome of patients with microsatellite instability (MSI) remains controversial. This...

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Vydáno v:PLoS One
Hlavní autoři: Haruma, Tomoko, Nagasaka, Takeshi, Nakamura, Keiichiro, Haraga, Junko, Nyuya, Akihiro, Nishida, Takeshi, Goel, Ajay, Masuyama, Hisashi, Hiramatsu, Yuji
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2018
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5901772/
https://ncbi.nlm.nih.gov/pubmed/29659608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0195655
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