Clinical impact of endometrial cancer stratified by genetic mutational profiles, POLE mutation, and microsatellite instability

BACKGROUND: The molecular characterization of endometrial cancer (EC) can facilitate identification of various tumor subtypes. Although EC patients with POLE mutations reproducibly demonstrate better prognosis, the outcome of patients with microsatellite instability (MSI) remains controversial. This...

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Dades bibliogràfiques
Publicat a:PLoS One
Autors principals: Haruma, Tomoko, Nagasaka, Takeshi, Nakamura, Keiichiro, Haraga, Junko, Nyuya, Akihiro, Nishida, Takeshi, Goel, Ajay, Masuyama, Hisashi, Hiramatsu, Yuji
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2018
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5901772/
https://ncbi.nlm.nih.gov/pubmed/29659608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0195655
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