Clinical impact of endometrial cancer stratified by genetic mutational profiles, POLE mutation, and microsatellite instability

BACKGROUND: The molecular characterization of endometrial cancer (EC) can facilitate identification of various tumor subtypes. Although EC patients with POLE mutations reproducibly demonstrate better prognosis, the outcome of patients with microsatellite instability (MSI) remains controversial. This...

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Detalles Bibliográficos
Publicado en:PLoS One
Main Authors: Haruma, Tomoko, Nagasaka, Takeshi, Nakamura, Keiichiro, Haraga, Junko, Nyuya, Akihiro, Nishida, Takeshi, Goel, Ajay, Masuyama, Hisashi, Hiramatsu, Yuji
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2018
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5901772/
https://ncbi.nlm.nih.gov/pubmed/29659608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0195655
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