Clinical impact of endometrial cancer stratified by genetic mutational profiles, POLE mutation, and microsatellite instability

BACKGROUND: The molecular characterization of endometrial cancer (EC) can facilitate identification of various tumor subtypes. Although EC patients with POLE mutations reproducibly demonstrate better prognosis, the outcome of patients with microsatellite instability (MSI) remains controversial. This...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Haruma, Tomoko, Nagasaka, Takeshi, Nakamura, Keiichiro, Haraga, Junko, Nyuya, Akihiro, Nishida, Takeshi, Goel, Ajay, Masuyama, Hisashi, Hiramatsu, Yuji
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5901772/
https://ncbi.nlm.nih.gov/pubmed/29659608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0195655
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