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Loss of INK4a/Arf gene enhances ultraviolet radiation induced cutaneous tumor development

The CDKN2A locus encodes for tumor suppressor genes p16(INK4a) and p14(Arf) which are frequently inactivated in human skin tumors. The purpose of this study was to determine the relationship between loss of INK4a/Arf activity and inflammation in the development of ultraviolet (UV) radiation-induced...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Exp Dermatol
Prif Awduron: Ahmad, Israr, Guroji, Purushotham, DeBrot, Amanda H., Manapragada, Padma P., Katiyar, Santosh K., Elmets, Craig A., Yusuf, Nabiha
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2017
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5901725/
https://ncbi.nlm.nih.gov/pubmed/28418604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/exd.13356
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