Loss of INK4a/Arf gene enhances ultraviolet radiation induced cutaneous tumor development

The CDKN2A locus encodes for tumor suppressor genes p16(INK4a) and p14(Arf) which are frequently inactivated in human skin tumors. The purpose of this study was to determine the relationship between loss of INK4a/Arf activity and inflammation in the development of ultraviolet (UV) radiation-induced...

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Bibliographic Details
Published in:Exp Dermatol
Main Authors: Ahmad, Israr, Guroji, Purushotham, DeBrot, Amanda H., Manapragada, Padma P., Katiyar, Santosh K., Elmets, Craig A., Yusuf, Nabiha
Format: Artigo
Language:Inglês
Published: 2017
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5901725/
https://ncbi.nlm.nih.gov/pubmed/28418604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/exd.13356
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