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The immunosuppressive effects of phthalocyanine photodynamic therapy in mice are mediated by CD4+ and CD8+ T cells and can be adoptively transferred to naïve recipients

Photodynamic therapy (PDT) is a promising treatment modality for malignant tumors but it is also immunosuppressive which may reduce its therapeutic efficacy. The purpose of our study was to elucidate the role of CD4+ and CD8+ T-cells in PDT immunosuppression. Using silicon phthalocyanine 4 (Pc4) as...

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Detalhes bibliográficos
Main Authors: Yusuf, Nabiha, Katiyar, Santosh K, Elmets, Craig A
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3768290/
https://ncbi.nlm.nih.gov/pubmed/18208456
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1751-1097.2007.00270.x
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