The TLR3 agonist poly(I:C) targets CD8+ T cells and augments their antigen-specific responses upon their adoptive transfer into naïve recipient mice

We have recently reported that the toll-like receptor 3 (TLR3) agonist poly(I:C) induces adjuvant effects to post vaccination CD8+ T cells responses through rapid induction of innate mediators, including NK cells, macrophages, dendritic cells (DCs), and inflammatory cytokines. However, whether this...

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Hlavní autoři: Salem, Mohamed L., Diaz-Montero, C. Marcela, EL-Naggar, Sabry A., Chen, Yian, Moussa, Omar, Cole, David J.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2008
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3072892/
https://ncbi.nlm.nih.gov/pubmed/19027047
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2008.11.013
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