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Priming of naive CD8+ T cells in the presence of IL-12 selectively enhances the survival of CD8(+)CD62L(hi) cells and results in superior anti-tumor activity in a tolerogenic murine model
During the antigen-dependant activation process several subsets CD8(+) T cells appear with different phenotypic and functional characteristics. Recent studies indicate that the state of T cell differentiation radically affects their ability to effectively respond to tumor challenge, with early effec...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3406410/ https://ncbi.nlm.nih.gov/pubmed/17726606 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00262-007-0394-0 |
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