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Reduced naïve CD8(+) T‐cell priming efficacy in elderly adults
Aging is associated with impaired vaccine efficacy and increased susceptibility to infectious and malignant diseases. CD8(+) T‐cells are key players in the immune response against pathogens and tumors. In aged mice, the dwindling naïve CD8(+) T‐cell compartment is thought to compromise the induction...
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| Pubblicato in: | Aging Cell |
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| Autori principali: | , , , , , , , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
John Wiley and Sons Inc.
2015
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4717282/ https://ncbi.nlm.nih.gov/pubmed/26472076 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12384 |
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