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Priming of qualitatively superior human effector CD8(+) T cells using TLR8 ligand combined with FLT3L()

The quality of antigen specific CD8(+) T cell responses is central to immune efficacy in infectious and malignant settings. Inducing effector CD8(+) T cells with potent functional properties is therefore a priority of immunotherapy. However, the optimal assessment of new therapeutic molecules or str...

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Detalhes bibliográficos
Publicado no:J Immunol
Main Authors: Lissina, Anna, Briceño, Olivia, Afonso, Georgia, Larsen, Martin, Gostick, Emma, Price, David A, Mallone, Roberto, Appay, Victor
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4685747/
https://ncbi.nlm.nih.gov/pubmed/26608912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1501140
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