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TLR4 ligands LPS and MPLA differentially regulate effector and memory CD8(+) T cell differentiation

Vaccines formulated with non-replicating pathogens require adjuvants to help bolster immunogenicity. The role of adjuvants in antibody production has been well studied, but how they influence memory CD8(+) T cell differentiation remains poorly defined. Here we implemented dendritic cell (DC)-mediate...

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書誌詳細
主要な著者: Cui, Weiguo, Joshi, Nikhil S., Liu, Ying, Meng, Hailong, Kleinstein, Steven H, Kaech, Susan M.
フォーマット: Artigo
言語:Inglês
出版事項: 2014
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4071140/
https://ncbi.nlm.nih.gov/pubmed/24659688
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1302569
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