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TLR4 ligands LPS and MPLA differentially regulate effector and memory CD8(+) T cell differentiation
Vaccines formulated with non-replicating pathogens require adjuvants to help bolster immunogenicity. The role of adjuvants in antibody production has been well studied, but how they influence memory CD8(+) T cell differentiation remains poorly defined. Here we implemented dendritic cell (DC)-mediate...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4071140/ https://ncbi.nlm.nih.gov/pubmed/24659688 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1302569 |
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