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Proanthocyanidins Inhibit UV-Induced Immunosuppression Through IL-12-Dependent Stimulation of CD8(+) Effector T Cells and Inactivation of CD4(+) T Cells

The inhibition of UVB-induced immunosuppression by dietary grape seed proanthocyanidins (GSPs) has been associated with the induction of interleukin (IL)-12 in mice and we now confirm that GSPs do not inhibit UVB-induced immunosuppression in IL-12p40 knock out (IL-12-KO) mice and that treatment of t...

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Detalhes bibliográficos
Main Authors: Vaid, Mudit, Singh, Tripti, Li, Anna, Katiyar, Nandan, Sharma, Samriti, Elmets, Craig A., Xu, Hui, Katiyar, Santosh K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3033965/
https://ncbi.nlm.nih.gov/pubmed/21075976
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1940-6207.CAPR-10-0224
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