High dietary fat and sucrose result in an extensive and time-dependent deterioration in health of multiple physiological systems in mice

Obesity is associated with metabolic dysfunction, including insulin resistance and hyperinsulinemia, and with disorders such as cardiovascular disease, osteoporosis, and neurodegeneration. Typically, these pathologies are examined in discrete model systems and with limited temporal resolution, and w...

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Bibliografiset tiedot
Julkaisussa:J Biol Chem
Päätekijät: Burchfield, James G., Kebede, Melkam A., Meoli, Christopher C., Stöckli, Jacqueline, Whitworth, P. Tess, Wright, Amanda L., Hoffman, Nolan J., Minard, Annabel Y., Ma, Xiuquan, Krycer, James R., Nelson, Marin E., Tan, Shi-Xiong, Yau, Belinda, Thomas, Kristen C., Wee, Natalie K. Y., Khor, Ee-Cheng, Enriquez, Ronaldo F., Vissel, Bryce, Biden, Trevor J., Baldock, Paul A., Hoehn, Kyle L., Cantley, James, Cooney, Gregory J., James, David E., Fazakerley, Daniel J.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Biochemistry and Molecular Biology 2018
Aiheet:
Metabolism
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5900752/
https://ncbi.nlm.nih.gov/pubmed/29440390
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA117.000808
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