An inactivating mutation in the histone deacetylase SIRT6 causes human perinatal lethality

It has been well established that histone and DNA modifications are critical to maintaining the equilibrium between pluripotency and differentiation during early embryogenesis. Mutations in key regulators of DNA methylation have shown that the balance between gene regulation and function is critical...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Genes Dev
Main Authors: Ferrer, Christina M., Alders, Marielle, Postma, Alex V., Park, Seonmi, Klein, Mark A., Cetinbas, Murat, Pajkrt, Eva, Glas, Astrid, van Koningsbruggen, Silvana, Christoffels, Vincent M., Mannens, Marcel M.A.M., Knegt, Lia, Etchegaray, Jean-Pierre, Sadreyev, Ruslan I., Denu, John M., Mostoslavsky, Gustavo, van Maarle, Merel C., Mostoslavsky, Raul
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2018
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5900711/
https://ncbi.nlm.nih.gov/pubmed/29555651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.307330.117
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados