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Lumacaftor (VX-809) restores the ability of CF macrophages to phagocytose and kill Pseudomonas aeruginosa
Cystic fibrosis (CF), the most common lethal genetic disease in Caucasians, is characterized by chronic bacterial lung infection and excessive inflammation, which lead to progressive loss of lung function and premature death. Although ivacaftor (VX-770) alone and ivacaftor in combination with lumaca...
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| Vydáno v: | Am J Physiol Lung Cell Mol Physiol |
|---|---|
| Hlavní autoři: | , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
American Physiological Society
2018
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5900360/ https://ncbi.nlm.nih.gov/pubmed/29146575 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00461.2017 |
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