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Lumacaftor (VX-809) restores the ability of CF macrophages to phagocytose and kill Pseudomonas aeruginosa

Cystic fibrosis (CF), the most common lethal genetic disease in Caucasians, is characterized by chronic bacterial lung infection and excessive inflammation, which lead to progressive loss of lung function and premature death. Although ivacaftor (VX-770) alone and ivacaftor in combination with lumaca...

詳細記述

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書誌詳細
出版年:Am J Physiol Lung Cell Mol Physiol
主要な著者: Barnaby, Roxanna, Koeppen, Katja, Nymon, Amanda, Hampton, Thomas H., Berwin, Brent, Ashare, Alix, Stanton, Bruce A.
フォーマット: Artigo
言語:Inglês
出版事項: American Physiological Society 2018
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5900360/
https://ncbi.nlm.nih.gov/pubmed/29146575
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00461.2017
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