A carregar...
The CFTR Corrector, VX-809 (Lumacaftor), Rescues ABCA4 Trafficking Mutants: a Potential Treatment for Stargardt Disease
BACKGROUND/AIMS: Mutations in ABCA4 cause Stargardt macular degeneration, which invariably ends in legal blindness. We studied two common mutants, A1038V (in NBD1) and G1961E (in NBD2), with the purpose of exploring how they interact with the cell’s quality control mechanism. The study was designed...
Na minha lista:
| Publicado no: | Cell Physiol Biochem |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7027368/ https://ncbi.nlm.nih.gov/pubmed/31403270 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.33594/000000146 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|