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CF monocyte-derived macrophages have an attenuated response to extracellular vesicles secreted by airway epithelial cells
Mutations in CFTR alter macrophage responses, for example, by reducing their ability to phagocytose and kill bacteria. Altered macrophage responses may facilitate bacterial infection and inflammation in the lungs, contributing to morbidity and mortality in cystic fibrosis (CF). Extracellular vesicle...
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| Publicado no: | Am J Physiol Lung Cell Mol Physiol |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Physiological Society
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8238154/ https://ncbi.nlm.nih.gov/pubmed/33471607 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00621.2020 |
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