CF monocyte-derived macrophages have an attenuated response to extracellular vesicles secreted by airway epithelial cells

Mutations in CFTR alter macrophage responses, for example, by reducing their ability to phagocytose and kill bacteria. Altered macrophage responses may facilitate bacterial infection and inflammation in the lungs, contributing to morbidity and mortality in cystic fibrosis (CF). Extracellular vesicle...

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Vydáno v:Am J Physiol Lung Cell Mol Physiol
Hlavní autoři: Koeppen, Katja, Nymon, Amanda, Barnaby, Roxanna, Li, Zhongyou, Hampton, Thomas H., Ashare, Alix, Stanton, Bruce A.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Physiological Society 2021
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8238154/
https://ncbi.nlm.nih.gov/pubmed/33471607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00621.2020
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