Interleukin-8 mediates neutrophil-endothelial interactions in pig-to-human xenogeneic models

BACKGROUND: Human neutrophils are sequestered by pig lung xenografts within minutes during ex vivo perfusion. This phenomenon is not prevented by pig genetic modifications that remove xeno-antigens or added human regulatory molecules intended to down-regulate activation of complement and coagulation...

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Detalhes bibliográficos
Publicado no:Xenotransplantation
Main Authors: French, Beth M., Sendil, Selin, Sepuru, Krishna Mohan, Ranek, Jolene, Burdorf, Lars, Harris, Donald, Redding, Emily, Cheng, Xiangfei, Laird, Christopher, Zhao, Yuming, Cerel, Benjamin, Rajarathnam, Krishna, Pierson, Richard N, Azimzadeh, Agnes M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5899681/
https://ncbi.nlm.nih.gov/pubmed/29427404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/xen.12385
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