Interleukin-8 mediates neutrophil-endothelial interactions in pig-to-human xenogeneic models

BACKGROUND: Human neutrophils are sequestered by pig lung xenografts within minutes during ex vivo perfusion. This phenomenon is not prevented by pig genetic modifications that remove xeno-antigens or added human regulatory molecules intended to down-regulate activation of complement and coagulation...

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Dettagli Bibliografici
Pubblicato in:Xenotransplantation
Autori principali: French, Beth M., Sendil, Selin, Sepuru, Krishna Mohan, Ranek, Jolene, Burdorf, Lars, Harris, Donald, Redding, Emily, Cheng, Xiangfei, Laird, Christopher, Zhao, Yuming, Cerel, Benjamin, Rajarathnam, Krishna, Pierson, Richard N, Azimzadeh, Agnes M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2018
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5899681/
https://ncbi.nlm.nih.gov/pubmed/29427404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/xen.12385
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