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Endothelial GqPCR activity controls capillary electrical signaling and brain blood flow through PIP(2) depletion
Brain capillaries play a critical role in sensing neural activity and translating it into dynamic changes in cerebral blood flow to serve the metabolic needs of the brain. The molecular cornerstone of this mechanism is the capillary endothelial cell inward rectifier K(+) (Kir2.1) channel, which is a...
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| Udgivet i: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2018
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5899484/ https://ncbi.nlm.nih.gov/pubmed/29581272 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1800201115 |
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