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RNA-mediated gene regulation is less evolvable than transcriptional regulation

Much of gene regulation is carried out by proteins that bind DNA or RNA molecules at specific sequences. One class of such proteins is transcription factors, which bind short DNA sequences to regulate transcription. Another class is RNA binding proteins, which bind short RNA sequences to regulate RN...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Payne, Joshua L., Khalid, Fahad, Wagner, Andreas
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5899451/
https://ncbi.nlm.nih.gov/pubmed/29581298
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1719138115
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