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Mechanisms of mutational robustness in transcriptional regulation

Robustness is the invariance of a phenotype in the face of environmental or genetic change. The phenotypes produced by transcriptional regulatory circuits are gene expression patterns that are to some extent robust to mutations. Here we review several causes of this robustness. They include robustne...

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Détails bibliographiques
Publié dans:Front Genet
Auteurs principaux: Payne, Joshua L., Wagner, Andreas
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4621482/
https://ncbi.nlm.nih.gov/pubmed/26579194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2015.00322
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