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RNA-mediated gene regulation is less evolvable than transcriptional regulation

Much of gene regulation is carried out by proteins that bind DNA or RNA molecules at specific sequences. One class of such proteins is transcription factors, which bind short DNA sequences to regulate transcription. Another class is RNA binding proteins, which bind short RNA sequences to regulate RN...

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Détails bibliographiques
Publié dans:Proc Natl Acad Sci U S A
Auteurs principaux: Payne, Joshua L., Khalid, Fahad, Wagner, Andreas
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5899451/
https://ncbi.nlm.nih.gov/pubmed/29581298
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1719138115
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