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Differential Delivery of Genomic Double-Stranded RNA Causes Reovirus Strain-Specific Differences in Interferon Regulatory Factor 3 Activation

Serotype 3 (T3) reoviruses induce substantially more type 1 interferon (IFN-I) secretion than serotype 1 (T1) strains. However, the mechanisms underlying differences in IFN-I production between T1 and T3 reoviruses remain undefined. Here, we found that differences in IFN-I production between T1 and...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Stuart, Johnasha D., Holm, Geoffrey H., Boehme, Karl W.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5899194/
https://ncbi.nlm.nih.gov/pubmed/29437975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01947-17
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