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Apoptosis Induced by Mammalian Reovirus Is Beta Interferon (IFN) Independent and Enhanced by IFN Regulatory Factor 3- and NF-κB-Dependent Expression of Noxa

A variety of signal transduction pathways are activated in response to viral infection, which dampen viral replication and transmission. These mechanisms involve both the induction of type I interferons (IFNs), which evoke an antiviral state, and the triggering of apoptosis. Mammalian orthoreoviruse...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Knowlton, Jonathan J., Dermody, Terence S., Holm, Geoffrey H.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3264342/
https://ncbi.nlm.nih.gov/pubmed/22090144
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.05924-11
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