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Treating cat allergy with monoclonal IgG antibodies that bind allergen and prevent IgE engagement
Acute allergic symptoms are caused by allergen-induced crosslinking of allergen-specific immunoglobulin E (IgE) bound to Fc-epsilon receptors on effector cells. Desensitization with allergen-specific immunotherapy (SIT) has been used for over a century, but the dominant protective mechanism remains...
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| Pubblicato in: | Nat Commun |
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| Autori principali: | , , , , , , , , , , , , , , , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Publishing Group UK
2018
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5897525/ https://ncbi.nlm.nih.gov/pubmed/29650949 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-03636-8 |
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