Allergen skin test reactivity and asthma are inversely associated with ratios of IgG4/IgE and total IgE/allergen‐specific IgE in Ugandan communities

BACKGROUND: Serum inhibition of allergen‐specific IgE has been associated with competing IgG4 and non‐specific polyclonal IgE. In allergen immunotherapy, beneficial responses have been associated with high IgG4/IgE ratios. Helminths potentiate antibody class switching to IgG4 and stimulate polyclona...

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Pubblicato in:Clin Exp Allergy
Autori principali: Nkurunungi, Gyaviira, Nassuuna, Jacent, Mpairwe, Harriet, Kabagenyi, Joyce, Nampijja, Margaret, Sanya, Richard E., Webb, Emily L., Elliott, Alison M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2021
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ORIGINAL ARTICLES
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7610822/
https://ncbi.nlm.nih.gov/pubmed/33512036
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cea.13834
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