Cross-reactive carbohydrate determinant-specific IgE obscures true atopy and exhibits α-1,3-fucose epitope-specific inverse associations with asthma

BACKGROUND: In high-income, temperate countries, IgE to allergen extracts is a risk factor for, and mediator of, allergy-related diseases (ARDs). In the tropics, positive IgE tests are also prevalent, but rarely associated with ARD. Instead, IgE responses to ubiquitous cross-reactive carbohydrate de...

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Publié dans:Allergy
Auteurs principaux: Nkurunungi, Gyaviira, Mpairwe, Harriet, Versteeg, Serge A., van Diepen, Angela, Nassuuna, Jacent, Kabagenyi, Joyce, Nambuya, Irene, Sanya, Richard E., Nampijja, Margaret, Serna, Sonia, Reichardt, Niels-Christian, Hokke, Cornelis H., Webb, Emily L., van Ree, Ronald, Yazdanbakhsh, Maria, Elliott, Alison M.
Format: Artigo
Langue:Inglês
Publié: 2021
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7610925/
https://ncbi.nlm.nih.gov/pubmed/32568414
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/all.14469
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