Efficacy of neratinib in the treatment of HER2/neu-amplified epithelial ovarian carcinoma in vitro and in vivo

Epithelial ovarian carcinoma is the most lethal of gynecologic malignancies. There is a need to optimize the currently available treatment strategies and to urgently develop novel therapeutic agents against chemotherapy-resistant disease. The objective of our study was to evaluate neratinib’s precli...

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Veröffentlicht in:Med Oncol
Hauptverfasser: Menderes, Gulden, Bonazzoli, Elena, Bellone, Stefania, Black, Jonathan D., Lopez, Salvatore, Pettinella, Francesca, Masserdotti, Alice, Zammataro, Luca, Litkouhi, Babak, Ratner, Elena, Silasi, Dan-Arin, Azodi, Masoud, Schwartz, Peter E., Santin, Alessandro D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2017
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5896014/
https://ncbi.nlm.nih.gov/pubmed/28397106
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12032-017-0956-8
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