Neratinib shows efficacy in the treatment of HER2 amplified carcinosarcoma in vitro and in vivo

OBJECTIVE: Carcinosarcoma is a deadly gynecologic malignancy with few effective treatment options. The study of new therapies is difficult because of its rarity. The objective of this study was to determine the efficacy of neratinib in the treatment of HER2 amplified carcinosarcoma. METHODS: The eff...

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Detalhes bibliográficos
Publicado no:Gynecol Oncol
Main Authors: Schwab, Carlton L., English, Diana P., Black, Jonathan, Bellone, Stefania, Lopez, Salvatore, Cocco, Emiliano, Bonazzoli, Elena, Bussi, Beatrice, Predolini, Federica, Ferrari, Francesca, Ratner, Elena, Silasi, Dan-Arin, Azodi, Masoud, Rutherford, Thomas, Schwartz, Peter E., Santin, Alessandro D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4587290/
https://ncbi.nlm.nih.gov/pubmed/26260909
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ygyno.2015.08.002
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