Neratinib shows efficacy in the treatment of HER2 amplified carcinosarcoma in vitro and in vivo

OBJECTIVE: Carcinosarcoma is a deadly gynecologic malignancy with few effective treatment options. The study of new therapies is difficult because of its rarity. The objective of this study was to determine the efficacy of neratinib in the treatment of HER2 amplified carcinosarcoma. METHODS: The eff...

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Gepubliceerd in:Gynecol Oncol
Hoofdauteurs: Schwab, Carlton L., English, Diana P., Black, Jonathan, Bellone, Stefania, Lopez, Salvatore, Cocco, Emiliano, Bonazzoli, Elena, Bussi, Beatrice, Predolini, Federica, Ferrari, Francesca, Ratner, Elena, Silasi, Dan-Arin, Azodi, Masoud, Rutherford, Thomas, Schwartz, Peter E., Santin, Alessandro D.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2015
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4587290/
https://ncbi.nlm.nih.gov/pubmed/26260909
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ygyno.2015.08.002
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