Host-mediated selection impacts the diversity of Plasmodium falciparum antigens within infections

Host immunity exerts strong selective pressure on pathogens. Population-level genetic analysis can identify signatures of this selection, but these signatures reflect the net selective effect of all hosts and vectors in a population. In contrast, analysis of pathogen diversity within hosts provides...

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Publicado no:Nat Commun
Main Authors: Early, Angela M., Lievens, Marc, MacInnis, Bronwyn L., Ockenhouse, Christian F., Volkman, Sarah K., Adjei, Samuel, Agbenyega, Tsiri, Ansong, Daniel, Gondi, Stacey, Greenwood, Brian, Hamel, Mary, Odero, Chris, Otieno, Kephas, Otieno, Walter, Owusu-Agyei, Seth, Asante, Kwaku Poku, Sorgho, Hermann, Tina, Lucas, Tinto, Halidou, Valea, Innocent, Wirth, Dyann F., Neafsey, Daniel E.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5895824/
https://ncbi.nlm.nih.gov/pubmed/29643376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-03807-7
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