Safety profile of the RTS,S/AS01 malaria vaccine in infants and children: additional data from a phase III randomized controlled trial in sub-Saharan Africa

A phase III, double-blind, randomized, controlled trial (NCT00866619) in sub-Saharan Africa showed RTS,S/AS01 vaccine efficacy against malaria. We now present in-depth safety results from this study. 8922 children (enrolled at 5–17 months) and 6537 infants (enrolled at 6–12 weeks) were 1:1:1-randomi...

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Detalhes bibliográficos
Publicado no:Hum Vaccin Immunother
Main Authors: Guerra Mendoza, Yolanda, Garric, Elodie, Leach, Amanda, Lievens, Marc, Ofori-Anyinam, Opokua, Pirçon, Jean-Yves, Stegmann, Jens-Ulrich, Vandoolaeghe, Pascale, Otieno, Lucas, Otieno, Walter, Owusu-Agyei, Seth, Sacarlal, Jahit, Masoud, Nahya Salim, Sorgho, Hermann, Tanner, Marcel, Tinto, Halidou, Valea, Innocent, Mtoro, Ali Takadir, Njuguna, Patricia, Oneko, Martina, Otieno, Godfrey Allan, Otieno, Kephas, Gesase, Samwel, Hamel, Mary J, Hoffman, Irving, Kaali, Seyram, Kamthunzi, Portia, Kremsner, Peter, Lanaspa, Miguel, Lell, Bertrand, Lusingu, John, Malabeja, Anangisye, Aide, Pedro, Akoo, Pauline, Ansong, Daniel, Asante, Kwaku Poku, Berkley, James A, Adjei, Samuel, Agbenyega, Tsiri, Agnandji, Selidji Todagbe, Schuerman, Lode
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2019
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6816384/
https://ncbi.nlm.nih.gov/pubmed/31012786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21645515.2019.1586040
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