Accurate estimation of 5-methylcytosine in mammalian mitochondrial DNA

Whilst 5-methylcytosine (5mC) is a major epigenetic mark in the nuclear DNA in mammals, whether or not mitochondrial DNA (mtDNA) receives 5mC modification remains controversial. Herein, we exhaustively analysed mouse mtDNA using three methods that are based upon different principles for detecting 5m...

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發表在:Sci Rep
Main Authors: Matsuda, Shigeru, Yasukawa, Takehiro, Sakaguchi, Yuriko, Ichiyanagi, Kenji, Unoki, Motoko, Gotoh, Kazuhito, Fukuda, Kei, Sasaki, Hiroyuki, Suzuki, Tsutomu, Kang, Dongchon
格式: Artigo
語言:Inglês
出版: Nature Publishing Group UK 2018
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5895755/
https://ncbi.nlm.nih.gov/pubmed/29643477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-24251-z
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