Selective stabilization of mammalian microRNAs by 3′ adenylation mediated by the cytoplasmic poly(A) polymerase GLD-2

The steady-state levels of microRNAs (miRNAs) and their activities are regulated by the post-transcriptional processes. It is known that 3′ ends of several miRNAs undergo post-dicing adenylation or uridylation. We isolated the liver-specific miR-122 from human hepatocytes and mouse livers. Direct an...

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Detalhes bibliográficos
Main Authors: Katoh, Takayuki, Sakaguchi, Yuriko, Miyauchi, Kenjyo, Suzuki, Takeo, Kashiwabara, Shin-ichi, Baba, Tadashi, Suzuki, Tsutomu
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2009
Assuntos:
Research Communication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2648654/
https://ncbi.nlm.nih.gov/pubmed/19240131
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1761509
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