Accurate estimation of 5-methylcytosine in mammalian mitochondrial DNA

Whilst 5-methylcytosine (5mC) is a major epigenetic mark in the nuclear DNA in mammals, whether or not mitochondrial DNA (mtDNA) receives 5mC modification remains controversial. Herein, we exhaustively analysed mouse mtDNA using three methods that are based upon different principles for detecting 5m...

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Bibliografiska uppgifter
I publikationen:Sci Rep
Huvudupphovsmän: Matsuda, Shigeru, Yasukawa, Takehiro, Sakaguchi, Yuriko, Ichiyanagi, Kenji, Unoki, Motoko, Gotoh, Kazuhito, Fukuda, Kei, Sasaki, Hiroyuki, Suzuki, Tsutomu, Kang, Dongchon
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group UK 2018
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5895755/
https://ncbi.nlm.nih.gov/pubmed/29643477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-24251-z
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