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Post-transcriptional Regulation of UGT2B10 Hepatic Expression and Activity by Alternative Splicing
The detoxification enzyme UDP-glucuronosyltransferase UGT2B10 is specialized in the N-linked glucuronidation of many drugs and xenobiotics. Preferred substrates possess tertiary aliphatic amines and heterocyclic amines, such as tobacco carcinogens and several antidepressants and antipsychotics. We h...
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| Опубликовано в: : | Drug Metab Dispos |
|---|---|
| Главные авторы: | , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
The American Society for Pharmacology and Experimental
Therapeutics
2018
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5894810/ https://ncbi.nlm.nih.gov/pubmed/29438977 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/dmd.117.079921 |
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