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Crystal structure of pyrimidine-nucleoside phosphorylase from Bacillus subtilis in complex with imidazole and sulfate

Pyrimidine-nucleoside phosphorylase catalyzes the phosphorolytic cleavage of thymidine and uridine with equal activity. Investigation of this protein is essential for anticancer drug design. Here, the structure of this protein from Bacillus subtilis in complex with imidazole and sulfate is reported...

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Detalles Bibliográficos
Publicado en:Acta Crystallogr F Struct Biol Commun
Main Authors: Balaev, V. V., Prokofev, I. I., Gabdoulkhakov, A. G., Betzel, C., Lashkov, A. A.
Formato: Artigo
Idioma:Inglês
Publicado: International Union of Crystallography 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5894104/
https://ncbi.nlm.nih.gov/pubmed/29633966
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S2053230X18002935
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