Crystal structure of pyrimidine-nucleoside phosphorylase from Bacillus subtilis in complex with imidazole and sulfate

Pyrimidine-nucleoside phosphorylase catalyzes the phosphorolytic cleavage of thymidine and uridine with equal activity. Investigation of this protein is essential for anticancer drug design. Here, the structure of this protein from Bacillus subtilis in complex with imidazole and sulfate is reported...

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Bibliographic Details
Published in:Acta Crystallogr F Struct Biol Commun
Main Authors: Balaev, V. V., Prokofev, I. I., Gabdoulkhakov, A. G., Betzel, C., Lashkov, A. A.
Format: Artigo
Language:Inglês
Published: International Union of Crystallography 2018
Subjects:
Research Communications
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5894104/
https://ncbi.nlm.nih.gov/pubmed/29633966
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S2053230X18002935
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