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Crystal structure of pyrimidine-nucleoside phosphorylase from Bacillus subtilis in complex with imidazole and sulfate

Pyrimidine-nucleoside phosphorylase catalyzes the phosphorolytic cleavage of thymidine and uridine with equal activity. Investigation of this protein is essential for anticancer drug design. Here, the structure of this protein from Bacillus subtilis in complex with imidazole and sulfate is reported...

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Veröffentlicht in:Acta Crystallogr F Struct Biol Commun
Hauptverfasser: Balaev, V. V., Prokofev, I. I., Gabdoulkhakov, A. G., Betzel, C., Lashkov, A. A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: International Union of Crystallography 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5894104/
https://ncbi.nlm.nih.gov/pubmed/29633966
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S2053230X18002935
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