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Crystal structure of pyrimidine-nucleoside phosphorylase from Bacillus subtilis in complex with imidazole and sulfate

Pyrimidine-nucleoside phosphorylase catalyzes the phosphorolytic cleavage of thymidine and uridine with equal activity. Investigation of this protein is essential for anticancer drug design. Here, the structure of this protein from Bacillus subtilis in complex with imidazole and sulfate is reported...

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Bibliografski detalji
Izdano u:Acta Crystallogr F Struct Biol Commun
Glavni autori: Balaev, V. V., Prokofev, I. I., Gabdoulkhakov, A. G., Betzel, C., Lashkov, A. A.
Format: Artigo
Jezik:Inglês
Izdano: International Union of Crystallography 2018
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5894104/
https://ncbi.nlm.nih.gov/pubmed/29633966
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S2053230X18002935
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