Quantity of Vaccine Poliovirus Shed Determines the Titer of the Serum Neutralizing Antibody Response in Indian Children Who Received Oral Vaccine

Replication of oral poliovirus vaccine (OPV) in the intestine (ie, vaccine take) is associated with seroconversion and protection against poliomyelitis. We used quantitative polymerase chain reaction analysis to measure vaccine shedding in 300 seronegative infants aged 6–11 months and in 218 childre...

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Bibliographische Detailangaben
Veröffentlicht in:J Infect Dis
Hauptverfasser: Giri, Sidhartha, Kumar, Nirmal, Dhanapal, Pavithra, Venkatesan, Jayalakshmi, Kasirajan, Anand, Iturriza-Gomara, Miren, John, Jacob, Abraham, Asha Mary, Grassly, Nicholas C, Kang, Gagandeep
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2018
Schlagworte:
Major Articles and Brief Reports
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5894085/
https://ncbi.nlm.nih.gov/pubmed/29300947
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jix687
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