Quantity of Vaccine Poliovirus Shed Determines the Titer of the Serum Neutralizing Antibody Response in Indian Children Who Received Oral Vaccine

Replication of oral poliovirus vaccine (OPV) in the intestine (ie, vaccine take) is associated with seroconversion and protection against poliomyelitis. We used quantitative polymerase chain reaction analysis to measure vaccine shedding in 300 seronegative infants aged 6–11 months and in 218 childre...

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Dettagli Bibliografici
Pubblicato in:J Infect Dis
Autori principali: Giri, Sidhartha, Kumar, Nirmal, Dhanapal, Pavithra, Venkatesan, Jayalakshmi, Kasirajan, Anand, Iturriza-Gomara, Miren, John, Jacob, Abraham, Asha Mary, Grassly, Nicholas C, Kang, Gagandeep
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2018
Soggetti:
Major Articles and Brief Reports
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5894085/
https://ncbi.nlm.nih.gov/pubmed/29300947
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jix687
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