Quantity of Vaccine Poliovirus Shed Determines the Titer of the Serum Neutralizing Antibody Response in Indian Children Who Received Oral Vaccine

Replication of oral poliovirus vaccine (OPV) in the intestine (ie, vaccine take) is associated with seroconversion and protection against poliomyelitis. We used quantitative polymerase chain reaction analysis to measure vaccine shedding in 300 seronegative infants aged 6–11 months and in 218 childre...

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Detalles Bibliográficos
Publicado en:J Infect Dis
Main Authors: Giri, Sidhartha, Kumar, Nirmal, Dhanapal, Pavithra, Venkatesan, Jayalakshmi, Kasirajan, Anand, Iturriza-Gomara, Miren, John, Jacob, Abraham, Asha Mary, Grassly, Nicholas C, Kang, Gagandeep
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2018
Assuntos:
Major Articles and Brief Reports
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5894085/
https://ncbi.nlm.nih.gov/pubmed/29300947
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jix687
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