Quantity of Vaccine Poliovirus Shed Determines the Titer of the Serum Neutralizing Antibody Response in Indian Children Who Received Oral Vaccine

Replication of oral poliovirus vaccine (OPV) in the intestine (ie, vaccine take) is associated with seroconversion and protection against poliomyelitis. We used quantitative polymerase chain reaction analysis to measure vaccine shedding in 300 seronegative infants aged 6–11 months and in 218 childre...

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Détails bibliographiques
Publié dans:J Infect Dis
Auteurs principaux: Giri, Sidhartha, Kumar, Nirmal, Dhanapal, Pavithra, Venkatesan, Jayalakshmi, Kasirajan, Anand, Iturriza-Gomara, Miren, John, Jacob, Abraham, Asha Mary, Grassly, Nicholas C, Kang, Gagandeep
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2018
Sujets:
Major Articles and Brief Reports
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5894085/
https://ncbi.nlm.nih.gov/pubmed/29300947
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jix687
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